- Generics contain the same active ingredient, strength and dosage form as the original brand.
- Regulators such as the FDA require generics to be bioequivalent to the brand.
- Inactive ingredients, colour and shape can differ.
- Ask your pharmacist whether a generic is available for your prescription.
What makes a medicine "generic"
The FDA explains that a generic medicine is created to be the same as an already marketed brand-name drug in dosage form, safety, strength, route of administration, quality, performance characteristics and intended use.
What bioequivalent means
The FDA explains that a generic must be bioequivalent to the brand — meaning it works in the same way and provides the same clinical benefit. Regulators review this evidence before approval; the FDA's generic-drugs pages explain the standard in detail.
Why generics usually cost less
Generic manufacturers do not repeat the original clinical trials, and competition between several manufacturers tends to lower prices.
When to talk to your clinician
For a small number of medicines your prescriber may prefer you stay on one specific product. If you are unsure, ask before switching.
Are generic medicines less safe?
No. Regulators hold approved generics to the same quality and safety standards as brand-name medicines.
Sources
- Generic Drugs: Questions & Answers — U.S. Food and Drug Administration